To ensure a smooth activation experience with KMSAuto, users must temporarily disable Windows Defender. This step is vital as Defender often perceives the activator as a threat due to its functionality. Although some may hesitate to disable their antivirus software, KMSAuto activators have a proven safety record with numerous users attesting to their reliability. It is advisable, however, to enable Windows Defender once the activation process is complete to maintain ongoing protection for your system.